Solutions for Pharma DMPK – PROTAC Metabolite Identification

PROTAC is a new class of compounds that tend to have quite a large structure and their metabolic studies could be challenging. Here we are presenting the use of MassMetaSite / WebMetabase in the study of the in-vitro metabolism of a PROTAC compound showing the impact of the different settings in the output, from the point of view of peaks and structures detected to the time for processing the data.