Solutions for: Chemistry, Pharma DMPK, BioPharma, OMICS and computational chemistry If you want to attend to one or more than one of these webinars please go to Tickets and Registration *Central European Time Zone The sessions are recorded and will be repeated in...
Practical applications for Drug Discovery 2020 WEBINARS Agenda *Central European Time Zone Monday 16th November 2020 4:00 PM Introduction to the webinars. https://attendee.gotowebinar.com/register/1214653994789287948 Our vision for Mass Spec software development 4:15 PM Solutions for Chemistry https://attendee.gotowebinar.com/register/6095367418789644812 Late stage Functionalization automation of MS driven structure elucidation ...
Mass Spectrometry Imaging is an established and powerful MS technique that enables molecular mapping of tissues and cells finding widespread applications in academic, medical, and pharmaceutical industries. Through user-friendly implementation of image visualization and co-registration, univariate and multivariate image and spectral analysis, and for the...
The combination of high spatial resolution and throughput MALDI imaging capabilities with high-performance Trapped Ion-Mobility Spectrometry (TIMS) separations provides a uniquely tunable platform to address many challenges associated with advanced molecular imaging applications. The capabilities of such TIMS-based platform provide a critical need to the...
Tissue distribution studies of drug and drug metabolites is a key step in the drug development pipeline. Mass Spectrometry Imaging is an established and powerful MS technique that enables mapping of drugs and metabolites directly from tissue without target specific labels or reagents. To achieve...
Peptides therapeutics are gaining a significant role on the pharmaceutical market due to their high selectivity and efficacy. However, natural peptides often must be optimized to improve their ADME properties by cyclisation, introduction of chemically modified amino acids or other modifications. Moreover, they can be...
Peptides therapeutics are becoming increasingly important on the pharmaceutical market. However, it is known that peptide drugs bioavailability and stability are lower than for small molecules. It is highly important to understand peptide drug metabolism and optimize its clearance as it influences the drug safety...
In complicated chemical reactions, like synthesis of PROTACs, the accidental generation of undesired byproducts can occur even if the conditions are well controlled (i.e. the unexpected degradation of one of the products, the interaction of solvent, catalysts and impurities with reactants, etc.). Reaction Tracking workflow...
Waters UNIFI Scientific Information System encompasses data acquisition, processing, visualization, reporting, and other tools within a networked laboratory environment. Prior MassChemSite 3.0, data providing from UNIFI specific instruments, like VION or the latest BioAccord LC-MS System. In this talk we will show how to configure...
Over the last two decades, lipids have come to be understood as far more than merely components of cellular membranes and forms of energy storage. Indeed, their pivotal role in a variety of diseases including diabetes, obesity, heart diseases, cancer, or neurodegenerative diseases, is now...